Endocrine Abstracts

In patients with cirrhosis, levels of prolactin are often increased, which can be related to the disturbed metabolism of estrogens. According to recent results, prolactin presumably has its role as a factor for regeneration and the induction of growth-associated genes (e.g.: c-myc, c-fos, c-jun). To learn about the function of PRL in the pathogenesis of cirrhosis we focused on the conduct of the prolactin-receptor (PRL-R) during reconstruction from healthy liver parenchyma to ...